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Notch1/Hes1-PTEN/AKT/IL-17A feedback loop regulates Th17 cell differentiation in mouse psoriasis-like skin inflammation

IL-17A, the effector cytokine of T helper (Th) 17 cells, plays a crucial role in the pathogenesis of psoriasis. The Notch1 and PI3K/AKT signaling pathways are implicated in Th17 cell differentiation and IL-17A production. The present study aimed to evaluate the regulatory effect of the Notch1/hairy...

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Detalles Bibliográficos
Autores principales:	Lin, Ya-Wen, Li, Xin-Xin, Fu, Fang-Hui, Liu, Bin, Xing, Xiaoyun, Qi, Ruiqun, Ma, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175275/ https://www.ncbi.nlm.nih.gov/pubmed/35582997 http://dx.doi.org/10.3892/mmr.2022.12739

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