Dissection of multiple sclerosis genetics identifies B and CD4+ T cells as driver cell subsets

BACKGROUND: Multiple sclerosis (MS) is an autoimmune condition of the central nervous system with a well-characterized genetic background. Prior analyses of MS genetics have identified broad enrichments across peripheral immune cells, yet the driver immune subsets are unclear. RESULTS: We utilize ch...

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Detalles Bibliográficos
Autores principales: Guo, Michael H., Sama, Prashanth, LaBarre, Brenna A., Lokhande, Hrishikesh, Balibalos, John, Chu, Ci, Du, Xiaomi, Kheradpour, Pouya, Kim, Charles C., Oniskey, Taylor, Snyder, Thomas, Soghoian, Damien Z., Weiner, Howard L., Chitnis, Tanuja, Patsopoulos, Nikolaos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175345/
https://www.ncbi.nlm.nih.gov/pubmed/35672799
http://dx.doi.org/10.1186/s13059-022-02694-y

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