Cargando…

QuickPed: an online tool for drawing pedigrees and analysing relatedness

BACKGROUND: The ubiquity of pedigrees in many scientific areas calls for versatile and user-friendly software. Previously published online pedigree tools have limited support for complex pedigrees and do not provide analysis of relatedness between pedigree members. RESULTS: We introduce QuickPed, a...

Descripción completa

Detalles Bibliográficos
Autor principal: Vigeland, Magnus D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175388/
https://www.ncbi.nlm.nih.gov/pubmed/35672681
http://dx.doi.org/10.1186/s12859-022-04759-y
_version_ 1784722445641449472
author Vigeland, Magnus D.
author_facet Vigeland, Magnus D.
author_sort Vigeland, Magnus D.
collection PubMed
description BACKGROUND: The ubiquity of pedigrees in many scientific areas calls for versatile and user-friendly software. Previously published online pedigree tools have limited support for complex pedigrees and do not provide analysis of relatedness between pedigree members. RESULTS: We introduce QuickPed, a web application for interactive pedigree creation and analysis. It supports complex inbreeding and comes with a rich built-in library of common and interesting pedigrees. The program calculates all standard coefficients of relatedness, including inbreeding, kinship and identity coefficients, and offers specialised plots for visualising relatedness. It also implements a novel algorithm for describing pairwise relationships in words. CONCLUSION: QuickPed is a user-friendly pedigree tool aimed at researchers, case workers and teachers. It contains a number of features not found in other similar tools, and represents a significant addition to the body of pedigree software by making advanced relatedness analyses available for non-bioinformaticians. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12859-022-04759-y.
format Online
Article
Text
id pubmed-9175388
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-91753882022-06-09 QuickPed: an online tool for drawing pedigrees and analysing relatedness Vigeland, Magnus D. BMC Bioinformatics Research BACKGROUND: The ubiquity of pedigrees in many scientific areas calls for versatile and user-friendly software. Previously published online pedigree tools have limited support for complex pedigrees and do not provide analysis of relatedness between pedigree members. RESULTS: We introduce QuickPed, a web application for interactive pedigree creation and analysis. It supports complex inbreeding and comes with a rich built-in library of common and interesting pedigrees. The program calculates all standard coefficients of relatedness, including inbreeding, kinship and identity coefficients, and offers specialised plots for visualising relatedness. It also implements a novel algorithm for describing pairwise relationships in words. CONCLUSION: QuickPed is a user-friendly pedigree tool aimed at researchers, case workers and teachers. It contains a number of features not found in other similar tools, and represents a significant addition to the body of pedigree software by making advanced relatedness analyses available for non-bioinformaticians. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12859-022-04759-y. BioMed Central 2022-06-07 /pmc/articles/PMC9175388/ /pubmed/35672681 http://dx.doi.org/10.1186/s12859-022-04759-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Vigeland, Magnus D.
QuickPed: an online tool for drawing pedigrees and analysing relatedness
title QuickPed: an online tool for drawing pedigrees and analysing relatedness
title_full QuickPed: an online tool for drawing pedigrees and analysing relatedness
title_fullStr QuickPed: an online tool for drawing pedigrees and analysing relatedness
title_full_unstemmed QuickPed: an online tool for drawing pedigrees and analysing relatedness
title_short QuickPed: an online tool for drawing pedigrees and analysing relatedness
title_sort quickped: an online tool for drawing pedigrees and analysing relatedness
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175388/
https://www.ncbi.nlm.nih.gov/pubmed/35672681
http://dx.doi.org/10.1186/s12859-022-04759-y
work_keys_str_mv AT vigelandmagnusd quickpedanonlinetoolfordrawingpedigreesandanalysingrelatedness