Tauroursodeoxycholic acid (TUDCA) improves intestinal barrier function associated with TGR5-MLCK pathway and the alteration of serum metabolites and gut bacteria in weaned piglets

BACKGROUND: Tauroursodeoxycholic acid (TUDCA), a hydrophilic bile acid, is the main medicinal component of bear bile and is commonly used to treat a variety of hepatobiliary diseases. Meanwhile, TUDCA has been shown to modulate the intestinal barrier function and alleviate DSS-induced colitis in mic...

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Detalles Bibliográficos
Autores principales: Song, Min, Zhang, Fenglin, Fu, Yiming, Yi, Xin, Feng, Shengchun, Liu, Zhichang, Deng, Dun, Yang, Qiang, Yu, Miao, Zhu, Canjun, Zhu, Xiaotong, Wang, Lina, Gao, Ping, Shu, Gang, Ma, Xianyong, Jiang, Qingyan, Wang, Songbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175448/
https://www.ncbi.nlm.nih.gov/pubmed/35672805
http://dx.doi.org/10.1186/s40104-022-00713-3

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