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Quiescent Elongation of α-Synuclein Pre-form Fibrils Under Different Solution Conditions

The intracellular aggregation of α-synuclein in neurons/glia is considered to be a key step in the pathogenesis of synucleinopathy [including Parkinson’s disease (PD), dementia with Lewy body (DLB), multiple system atrophy (MSA), etc.]. Increasing evidence indicates that the initial pathological α-s...

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Detalles Bibliográficos
Autores principales: Mao, Hengxu, Ye, Yongyi, Sun, Xiang, Qian, Chen, Wang, Baoyan, Xie, Linghai, Zhang, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175570/
https://www.ncbi.nlm.nih.gov/pubmed/35692426
http://dx.doi.org/10.3389/fnins.2022.902077