Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands

Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up‐to‐date estimates of 5‐year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post‐diagnosis among CLL patients diagnosed...

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Autores principales: van der Straten, Lina, Levin, Mark‐David, Visser, Otto, Posthuma, Eduardus F.M., Doorduijn, Jeanette K., Kater, Arnon P., Dinmohamed, Avinash G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175753/
https://www.ncbi.nlm.nih.gov/pubmed/35846209
http://dx.doi.org/10.1002/jha2.368
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author van der Straten, Lina
Levin, Mark‐David
Visser, Otto
Posthuma, Eduardus F.M.
Doorduijn, Jeanette K.
Kater, Arnon P.
Dinmohamed, Avinash G.
author_facet van der Straten, Lina
Levin, Mark‐David
Visser, Otto
Posthuma, Eduardus F.M.
Doorduijn, Jeanette K.
Kater, Arnon P.
Dinmohamed, Avinash G.
author_sort van der Straten, Lina
collection PubMed
description Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up‐to‐date estimates of 5‐year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post‐diagnosis among CLL patients diagnosed during 2007–2020. We showed that 5‐year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel‐based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared to an age‐ and sex‐matched group from the general population.
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spelling pubmed-91757532022-07-14 Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands van der Straten, Lina Levin, Mark‐David Visser, Otto Posthuma, Eduardus F.M. Doorduijn, Jeanette K. Kater, Arnon P. Dinmohamed, Avinash G. EJHaem Short Reports Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up‐to‐date estimates of 5‐year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post‐diagnosis among CLL patients diagnosed during 2007–2020. We showed that 5‐year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel‐based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared to an age‐ and sex‐matched group from the general population. John Wiley and Sons Inc. 2021-12-20 /pmc/articles/PMC9175753/ /pubmed/35846209 http://dx.doi.org/10.1002/jha2.368 Text en © 2021 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Reports
van der Straten, Lina
Levin, Mark‐David
Visser, Otto
Posthuma, Eduardus F.M.
Doorduijn, Jeanette K.
Kater, Arnon P.
Dinmohamed, Avinash G.
Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands
title Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands
title_full Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands
title_fullStr Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands
title_full_unstemmed Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands
title_short Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands
title_sort conditional relative survival among patients with chronic lymphocytic leukaemia: a population‐based study in the netherlands
topic Short Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175753/
https://www.ncbi.nlm.nih.gov/pubmed/35846209
http://dx.doi.org/10.1002/jha2.368
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