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Crystallization of ApoA1 and ApoE4 nanolipoprotein particles and initial XFEL-based structural studies

Nanolipoprotein particles (NLPs), also called “nanodiscs”, are discoidal particles with a patch of lipid bilayer corralled by apolipoproteins. NLPs have long been of interest due to both their utility as membrane-model systems into which membrane proteins can be inserted and solubilized and their ph...

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Detalles Bibliográficos
Autores principales: Shelby, M.L., Gilbile, D., Grant, T.D., Bauer, W.J., Segelke, B., He, W., Evans, A.C., Crespo, N., Fischer, P., Pakendorf, T., Hennicke, V., Hunter, M.S., Batyuk, A., Barthelmess, M., Meents, A., Kuhl, T.L., Frank, M., Coleman, M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175823/
https://www.ncbi.nlm.nih.gov/pubmed/35686136
http://dx.doi.org/10.3390/cryst10100886