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Shortened Positive and Negative Symptom Scale as an Alternate Clinical Endpoint for Acute Schizophrenia Trials: Analysis from the US Food & Drug Administration

OBJECTIVE: To evaluate the performance of the individual Positive and Negative Symptom Scale (PANSS) items, and to assess the feasibility of using a shortened version of the PANSS as an alternative regulatory endpoint for evaluating the efficacy of drugs to treat schizophrenia. DESIGN: Data from 32...

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Detalles Bibliográficos
Autores principales: Gopalakrishnan, Mathangi, Farchione, Tiffany, Mathis, Mitchell, Zhu, Hao, Mehta, Mehul, Uppoor, Ramana, Younis, Islam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175851/
https://www.ncbi.nlm.nih.gov/pubmed/36101554
http://dx.doi.org/10.1176/appi.prcp.20200003

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