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A same‐day assay predicts apoptotic response to combined BCL‐2 and MCL‐1 BH3‐mimetic targeting in multiple myeloma cells

Recent advances in treatment options for multiple myeloma (MM) have positive impact on patient survival. However, there is a short fall of rapid and reliable assays that can predict patient response to novel agents. The anti‐apoptotic proteins B‐cell lymphoma‐2 (BCL‐2) and myeloid cell leukaemia‐1 (...

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Detalles Bibliográficos
Autores principales: Grundy, Martin, Al‐Kaisi, Firas, Cull, Joanna, Williams, Cathy, Smith, Dean, Seedhouse, Claire H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175957/
https://www.ncbi.nlm.nih.gov/pubmed/35846088
http://dx.doi.org/10.1002/jha2.133