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Genetic aberrations of NLRC5 are associated with downregulated MHC‐I antigen presentation and impaired T‐cell immunity in follicular lymphoma

Follicular lymphoma (FL) is the most common indolent non‐Hodgkin lymphoma. Twenty to twenty‐five percent of FL patients have progression of disease within 24 months. These patients may benefit from immunotherapy if intact antigen presentation is present. Molecular mechanisms impairing major histocom...

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Detalles Bibliográficos
Autores principales: Gunawardana, Jay, Lee, Justina N., Bednarska, Karolina, Murigneux, Valentine, de Long, Lilia Merida, Sabdia, Muhammed B., Birch, Simone, Tobin, Joshua W. D., Gandhi, Maher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176136/
https://www.ncbi.nlm.nih.gov/pubmed/35845006
http://dx.doi.org/10.1002/jha2.116