Cargando…
Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka
There are no published data on long‐term survival and applicability of treatment protocols from developed countries in acute myeloid leukaemia (AML) in Sri Lanka. Eighty‐seven AML patients were reviewed; there were 56 newly diagnosed patients between 18 and 65 years. Thirty‐one out of 33 who started...
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176152/ https://www.ncbi.nlm.nih.gov/pubmed/35844682 http://dx.doi.org/10.1002/jha2.191 |
| _version_ | 1784722602318626816 |
|---|---|
| author | Hewamana, Saman Kandabadage, Lakmali Skandarajah, Thurairajah Pieris, Natasha Perera, Eranga Harischandra, Mahesh Wijewickrama, Ananda Wickramarathna, Chandana Somasundaram, Gnani Srinivasan, Vadivelu Somiah, Surjit Jayawardena, Priyankara Perera, Mehendra Gunasekera, Dehan Jayasinghe, Chathuri Constantine, Godvin Munasinghe, Sanjeewa De Silva, Chandu Wijesiriwardena, Bandula Balawardena, Jayantha |
| author_facet | Hewamana, Saman Kandabadage, Lakmali Skandarajah, Thurairajah Pieris, Natasha Perera, Eranga Harischandra, Mahesh Wijewickrama, Ananda Wickramarathna, Chandana Somasundaram, Gnani Srinivasan, Vadivelu Somiah, Surjit Jayawardena, Priyankara Perera, Mehendra Gunasekera, Dehan Jayasinghe, Chathuri Constantine, Godvin Munasinghe, Sanjeewa De Silva, Chandu Wijesiriwardena, Bandula Balawardena, Jayantha |
| author_sort | Hewamana, Saman |
| collection | PubMed |
| description | There are no published data on long‐term survival and applicability of treatment protocols from developed countries in acute myeloid leukaemia (AML) in Sri Lanka. Eighty‐seven AML patients were reviewed; there were 56 newly diagnosed patients between 18 and 65 years. Thirty‐one out of 33 who started treatment achieved complete remission after first cycle of treatment. The induction mortality was one of 33. Twelve out of 20 patients who completed treatment are alive at the time of analysis. The estimated 5‐year overall survival rate is 0.629. Strict infection control and treatment and superior clinical experience may have contributed towards better outcome. |
| format | Online Article Text |
| id | pubmed-9176152 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-91761522022-07-14 Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka Hewamana, Saman Kandabadage, Lakmali Skandarajah, Thurairajah Pieris, Natasha Perera, Eranga Harischandra, Mahesh Wijewickrama, Ananda Wickramarathna, Chandana Somasundaram, Gnani Srinivasan, Vadivelu Somiah, Surjit Jayawardena, Priyankara Perera, Mehendra Gunasekera, Dehan Jayasinghe, Chathuri Constantine, Godvin Munasinghe, Sanjeewa De Silva, Chandu Wijesiriwardena, Bandula Balawardena, Jayantha EJHaem Case Reports There are no published data on long‐term survival and applicability of treatment protocols from developed countries in acute myeloid leukaemia (AML) in Sri Lanka. Eighty‐seven AML patients were reviewed; there were 56 newly diagnosed patients between 18 and 65 years. Thirty‐one out of 33 who started treatment achieved complete remission after first cycle of treatment. The induction mortality was one of 33. Twelve out of 20 patients who completed treatment are alive at the time of analysis. The estimated 5‐year overall survival rate is 0.629. Strict infection control and treatment and superior clinical experience may have contributed towards better outcome. John Wiley and Sons Inc. 2021-05-13 /pmc/articles/PMC9176152/ /pubmed/35844682 http://dx.doi.org/10.1002/jha2.191 Text en © 2021 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Case Reports Hewamana, Saman Kandabadage, Lakmali Skandarajah, Thurairajah Pieris, Natasha Perera, Eranga Harischandra, Mahesh Wijewickrama, Ananda Wickramarathna, Chandana Somasundaram, Gnani Srinivasan, Vadivelu Somiah, Surjit Jayawardena, Priyankara Perera, Mehendra Gunasekera, Dehan Jayasinghe, Chathuri Constantine, Godvin Munasinghe, Sanjeewa De Silva, Chandu Wijesiriwardena, Bandula Balawardena, Jayantha Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka |
| title | Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka |
| title_full | Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka |
| title_fullStr | Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka |
| title_full_unstemmed | Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka |
| title_short | Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka |
| title_sort | applicability of western protocols in resource‐limited setting: real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in sri lanka |
| topic | Case Reports |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176152/ https://www.ncbi.nlm.nih.gov/pubmed/35844682 http://dx.doi.org/10.1002/jha2.191 |
| work_keys_str_mv | AT hewamanasaman applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT kandabadagelakmali applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT skandarajahthurairajah applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT pierisnatasha applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT pereraeranga applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT harischandramahesh applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT wijewickramaananda applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT wickramarathnachandana applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT somasundaramgnani applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT srinivasanvadivelu applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT somiahsurjit applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT jayawardenapriyankara applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT pereramehendra applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT gunasekeradehan applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT jayasinghechathuri applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT constantinegodvin applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT munasinghesanjeewa applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT desilvachandu applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT wijesiriwardenabandula applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka AT balawardenajayantha applicabilityofwesternprotocolsinresourcelimitedsettingrealworlddataoflongtermoutcomeofintensivetreatmentofadultacutemyeloidleukaemiainsrilanka |