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Effect of Genetic Variations in Drug-Metabolizing Enzymes and Drug Transporters on the Pharmacokinetics of Rifamycins: A Systematic Review

BACKGROUND: Rifamycins are a novel class of antibiotics clinically approved for tuberculosis chemotherapy. They are characterized by high inter-individual variation in pharmacokinetics. This systematic review aims to present the contribution of genetic variations in drug-metabolizing enzymes and tra...

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Detalles Bibliográficos
Autores principales:	Sileshi, Tesemma, Mekonen, Gosaye, Makonnen, Eyasu, Aklillu, Eleni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176238/ https://www.ncbi.nlm.nih.gov/pubmed/35693129 http://dx.doi.org/10.2147/PGPM.S363058

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