Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers

A novel series of 2-thioacetamide linked benzoxazole-benzamide conjugates 1–15 was designed as potential inhibitors of the vascular endothelial growth factor receptor-2 (VEGFR-2). The prepared compounds were evaluated for their potential antitumor activity and their corresponding selective cytotoxic...

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Detalles Bibliográficos
Autores principales: Eissa, Ibrahim H., El-Haggar, Radwan, Dahab, Mohammed A., Ahmed, Marwa F., Mahdy, Hazem A., Alsantali, Reem I., Elwan, Alaa, Masurier, Nicolas, Fatahala, Samar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176662/
https://www.ncbi.nlm.nih.gov/pubmed/35637622
http://dx.doi.org/10.1080/14756366.2022.2081844

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