ACE2 decoy receptor generated by high-throughput saturation mutagenesis efficiently neutralizes SARS-CoV-2 and its prevalent variants

The recent global pandemic was a spillover from the SARS-CoV-2 virus. Viral entry involves the receptor binding domain (RBD) of the viral spike protein interacting with the protease domain (PD) of the cellular receptor, ACE2. We hereby present a comprehensive mutational landscape of the effects of A...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Bolun, Zhao, Junxuan, Liu, Shuo, Feng, Jingyuan, Luo, Yufeng, He, Xinyu, Wang, Yanmin, Ge, Feixiang, Wang, Junyi, Ye, Buqing, Huang, Weijin, Bo, Xiaochen, Wang, Youchun, Xi, Jianzhong Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Coronaviruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176695/
https://www.ncbi.nlm.nih.gov/pubmed/35587428
http://dx.doi.org/10.1080/22221751.2022.2079426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176695/
https://www.ncbi.nlm.nih.gov/pubmed/35587428
http://dx.doi.org/10.1080/22221751.2022.2079426

Ejemplares similares