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ACE2 decoy receptor generated by high-throughput saturation mutagenesis efficiently neutralizes SARS-CoV-2 and its prevalent variants

The recent global pandemic was a spillover from the SARS-CoV-2 virus. Viral entry involves the receptor binding domain (RBD) of the viral spike protein interacting with the protease domain (PD) of the cellular receptor, ACE2. We hereby present a comprehensive mutational landscape of the effects of A...

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Detalles Bibliográficos
Autores principales:	Wang, Bolun, Zhao, Junxuan, Liu, Shuo, Feng, Jingyuan, Luo, Yufeng, He, Xinyu, Wang, Yanmin, Ge, Feixiang, Wang, Junyi, Ye, Buqing, Huang, Weijin, Bo, Xiaochen, Wang, Youchun, Xi, Jianzhong Jeff
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Coronaviruses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176695/ https://www.ncbi.nlm.nih.gov/pubmed/35587428 http://dx.doi.org/10.1080/22221751.2022.2079426

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