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A novel tumor-homing TRAIL variant eradicates tumor xenografts of refractory colorectal cancer cells in combination with tumor cell-targeted photodynamic therapy

Multidrug resistance (MDR), which is common in colorectal cancer (CRC), induces high mortality in patients. Due to its robust and selective apoptosis induction in some CRC cells with MDR, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is attractive as a novel tool for CRC therapy. H...

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Detalles Bibliográficos
Autores principales: Li, Zhao, She, Tianshan, Yang, Hao, Su, Tao, Shi, Qiuxiao, Tao, Ze, Feng, Yanru, Yang, Fen, Cheng, Jingqiu, Lu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176698/
https://www.ncbi.nlm.nih.gov/pubmed/35635308
http://dx.doi.org/10.1080/10717544.2022.2079766