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Investigating the structural changes due to adenosine methylation of the Kaposi’s sarcoma-associated herpes virus ORF50 transcript

Kaposi’s sarcoma-associated herpes virus (KSHV) is a human oncovirus. KSHV relies on manipulating the host cell N6-methyl adenosine (m6A) RNA modification pathway to enhance virus replication. Methylation within a RNA stem loop of the open reading frame 50 (ORF50) increases transcript stability via...

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Detalles Bibliográficos
Autores principales:	Röder, Konstantin, Barker, Amy M., Whitehouse, Adrian, Pasquali, Samuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176763/ https://www.ncbi.nlm.nih.gov/pubmed/35617364 http://dx.doi.org/10.1371/journal.pcbi.1010150

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