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A rapid and sensitive assay for quantifying the activity of both aerobic and anaerobic ribonucleotide reductases acting upon any or all substrates
Ribonucleotide reductases (RNRs) use radical-based chemistry to catalyze the conversion of all four ribonucleotides to deoxyribonucleotides. The ubiquitous nature of RNRs necessitates multiple RNR classes that differ from each other in terms of the phosphorylation state of the ribonucleotide substra...
Autores principales: | Levitz, Talya S., Andree, Gisele A., Jonnalagadda, Rohan, Dawson, Christopher D., Bjork, Rebekah E., Drennan, Catherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176816/ https://www.ncbi.nlm.nih.gov/pubmed/35675376 http://dx.doi.org/10.1371/journal.pone.0269572 |
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