Ca(v)1.3 calcium channels are full-range linear amplifiers of firing frequencies in lateral DA SN neurons

The low-threshold L-type calcium channel Ca(v)1.3 accelerates the pacemaker rate in the heart, but its functional role for the extended dynamic range of neuronal firing is still unresolved. Here, we show that Ca(v)1.3 calcium channels act as unexpectedly simple, full-range linear amplifiers of firin...

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Detalles Bibliográficos
Autores principales: Shin, Josef, Kovacheva, Lora, Thomas, Dominique, Stojanovic, Strahinja, Knowlton, Christopher J., Mankel, Johanna, Boehm, Johannes, Farassat, Navid, Paladini, Carlos, Striessnig, Jörg, Canavier, Carmen C., Geisslinger, Gerd, Roeper, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177074/
https://www.ncbi.nlm.nih.gov/pubmed/35675413
http://dx.doi.org/10.1126/sciadv.abm4560

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