Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors

BACKGROUND: Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UT) are aggressive neoplasms. Data linking BAF alterations with tumor microenvironment (TME) and efficacy of immune checkpoint inhibitors (ICI) are contradictory. The TME of SMARCA4-UT and their response to ICI are unknown. MATE...

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Detalles Bibliográficos
Autores principales: Gantzer, Justine, Davidson, Guillaume, Vokshi, Bujamin, Weingertner, Noëlle, Bougoüin, Antoine, Moreira, Marco, Lindner, Véronique, Lacroix, Guillaume, Mascaux, Céline, Chenard, Marie-Pierre, Bertucci, François, Davidson, Irwin, Kurtz, Jean-Emmanuel, Sautès-Fridman, Catherine, Fridman, Wolf H, Malouf, Gabriel G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Sarcomas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177113/
https://www.ncbi.nlm.nih.gov/pubmed/35278076
http://dx.doi.org/10.1093/oncolo/oyac040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177113/
https://www.ncbi.nlm.nih.gov/pubmed/35278076
http://dx.doi.org/10.1093/oncolo/oyac040

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