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Native Endophytes of Tripterygium wilfordii-Mediated Biotransformation Reduces Toxicity of Celastrol

Celastrol (1), obtained from the roots of Tripterygium wilfordii Hook F., is most likely to become an antitumor drug, but with severe cytotoxicity. Due to the lack of modifiable sites in the structure of celastrol, the structural diversity of the modified products obtained by synthesis in the previo...

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Detalles Bibliográficos
Autores principales:	Ma, Ping-yang, Geng, Wei-ling, Ji, Hong-yan, Yue, Bang-wen, Liu, Cheng, Wang, Sa, Jiang, Zhi-bo, Chen, Jing, Wu, Xiu-li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177160/ https://www.ncbi.nlm.nih.gov/pubmed/35694316 http://dx.doi.org/10.3389/fmicb.2022.810565

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