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Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age

Background: Patients with advanced lumbar spinal canal stenosis (LCS) often prefer non-operative treatment owing to decreased physiological function and comorbidities. Although the therapeutic value of selective nerve root block (SNRB) for LCS is confirmed, there are few reports of its effectiveness...

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Autores principales: Sakai, Mamiko, Inokuchi, Akihiko, Imamura, Ryuta, Izumi, Teiyu, Yamamoto, Masatoshi, Yoshimoto, Masakazu, Soejima, Yu, Nakamura, Kimitaka, Hamada, Takahiro, Arizono, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177313/
https://www.ncbi.nlm.nih.gov/pubmed/35702474
http://dx.doi.org/10.7759/cureus.24863
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author Sakai, Mamiko
Inokuchi, Akihiko
Imamura, Ryuta
Izumi, Teiyu
Yamamoto, Masatoshi
Yoshimoto, Masakazu
Soejima, Yu
Nakamura, Kimitaka
Hamada, Takahiro
Arizono, Takeshi
author_facet Sakai, Mamiko
Inokuchi, Akihiko
Imamura, Ryuta
Izumi, Teiyu
Yamamoto, Masatoshi
Yoshimoto, Masakazu
Soejima, Yu
Nakamura, Kimitaka
Hamada, Takahiro
Arizono, Takeshi
author_sort Sakai, Mamiko
collection PubMed
description Background: Patients with advanced lumbar spinal canal stenosis (LCS) often prefer non-operative treatment owing to decreased physiological function and comorbidities. Although the therapeutic value of selective nerve root block (SNRB) for LCS is confirmed, there are few reports of its effectiveness in the elderly. We investigated the efficacy of SNRB for LCS in patients over 80 years of age. Methods: The subjects were 112 patients aged over 80 years (mean age: 84 years; 45 men and 67 women ) with medication-resistant LCS without cauda equina syndrome who underwent SNRB. Cases with acute-onset lumbar disc herniation were excluded. We retrospectively investigated and compared the presence or absence of surgery, effect of SNRB, number of procedures, duration of disease, and magnetic resonance imaging findings. Patients who could avoid the surgery by SNRB were defined as the effective group. Patients whose symptoms were not relieved by SNRB and who underwent surgery and those whose symptoms were not relieved but who continued conservative treatment were defined as the ineffective group. A total of one to seven SNRBs were performed in both groups, and the same spine surgeon performed the entire procedure from SNRB to surgery. Results: There were 86 nonoperative patients (69 effective cases) and 26 operative patients; the overall rate of effectiveness was 61% (69/112 patients). The area of the spinal canal at the responsible level was 108.63 mm(2) in the effective group compared with 77.06 mm(2) in the ineffective group. This was significantly narrower in the ineffective group (p=0.0094). There was no significant difference in the duration of illness, number of blocks, or hernia complication rate between the groups. No patient experienced severe neuralgia that may have been caused by neuropathy during SNRB. Discussion: Our outcome showed that more than 60% of older patients with LCS showed symptomatic improvement with SNRB. SNRB can be performed relatively safely in the elderly and appears to be a favorable treatment option for older patients with various risks, such as poor general condition. Conclusions: Multiple sessions of SNRB may provide older patients with symptomatic improvement and may be an option for treatment.
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spelling pubmed-91773132022-06-13 Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age Sakai, Mamiko Inokuchi, Akihiko Imamura, Ryuta Izumi, Teiyu Yamamoto, Masatoshi Yoshimoto, Masakazu Soejima, Yu Nakamura, Kimitaka Hamada, Takahiro Arizono, Takeshi Cureus Orthopedics Background: Patients with advanced lumbar spinal canal stenosis (LCS) often prefer non-operative treatment owing to decreased physiological function and comorbidities. Although the therapeutic value of selective nerve root block (SNRB) for LCS is confirmed, there are few reports of its effectiveness in the elderly. We investigated the efficacy of SNRB for LCS in patients over 80 years of age. Methods: The subjects were 112 patients aged over 80 years (mean age: 84 years; 45 men and 67 women ) with medication-resistant LCS without cauda equina syndrome who underwent SNRB. Cases with acute-onset lumbar disc herniation were excluded. We retrospectively investigated and compared the presence or absence of surgery, effect of SNRB, number of procedures, duration of disease, and magnetic resonance imaging findings. Patients who could avoid the surgery by SNRB were defined as the effective group. Patients whose symptoms were not relieved by SNRB and who underwent surgery and those whose symptoms were not relieved but who continued conservative treatment were defined as the ineffective group. A total of one to seven SNRBs were performed in both groups, and the same spine surgeon performed the entire procedure from SNRB to surgery. Results: There were 86 nonoperative patients (69 effective cases) and 26 operative patients; the overall rate of effectiveness was 61% (69/112 patients). The area of the spinal canal at the responsible level was 108.63 mm(2) in the effective group compared with 77.06 mm(2) in the ineffective group. This was significantly narrower in the ineffective group (p=0.0094). There was no significant difference in the duration of illness, number of blocks, or hernia complication rate between the groups. No patient experienced severe neuralgia that may have been caused by neuropathy during SNRB. Discussion: Our outcome showed that more than 60% of older patients with LCS showed symptomatic improvement with SNRB. SNRB can be performed relatively safely in the elderly and appears to be a favorable treatment option for older patients with various risks, such as poor general condition. Conclusions: Multiple sessions of SNRB may provide older patients with symptomatic improvement and may be an option for treatment. Cureus 2022-05-09 /pmc/articles/PMC9177313/ /pubmed/35702474 http://dx.doi.org/10.7759/cureus.24863 Text en Copyright © 2022, Sakai et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Orthopedics
Sakai, Mamiko
Inokuchi, Akihiko
Imamura, Ryuta
Izumi, Teiyu
Yamamoto, Masatoshi
Yoshimoto, Masakazu
Soejima, Yu
Nakamura, Kimitaka
Hamada, Takahiro
Arizono, Takeshi
Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age
title Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age
title_full Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age
title_fullStr Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age
title_full_unstemmed Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age
title_short Efficacy of Nerve Root Block for the Treatment of Lumbar Spinal Canal Stenosis in Adults Older Than 80 Years of Age
title_sort efficacy of nerve root block for the treatment of lumbar spinal canal stenosis in adults older than 80 years of age
topic Orthopedics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177313/
https://www.ncbi.nlm.nih.gov/pubmed/35702474
http://dx.doi.org/10.7759/cureus.24863
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