Juvenile Hepatocellular Carcinoma in a Healthy Liver

Primary hepatocellular carcinoma (HCC) in patients ＜30 years old is extremely rare. In younger patients, HCC develops against a background of persistent hepatitis B virus infection. We herein report a 23-year-old woman with HCC with all-negative hepatitis virus markers developing in an apparently he...

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Autores principales: Onishi, Sachiyo, Tajika, Masahiro, Tanaka, Tsutomu, Yamada, Keisaku, Kamiya, Tomoyasu, Natsume, Seiji, Shimizu, Yasuhiro, Niwa, Yasumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177355/
https://www.ncbi.nlm.nih.gov/pubmed/34670900
http://dx.doi.org/10.2169/internalmedicine.8305-21
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author Onishi, Sachiyo
Tajika, Masahiro
Tanaka, Tsutomu
Yamada, Keisaku
Kamiya, Tomoyasu
Natsume, Seiji
Shimizu, Yasuhiro
Niwa, Yasumasa
author_facet Onishi, Sachiyo
Tajika, Masahiro
Tanaka, Tsutomu
Yamada, Keisaku
Kamiya, Tomoyasu
Natsume, Seiji
Shimizu, Yasuhiro
Niwa, Yasumasa
author_sort Onishi, Sachiyo
collection PubMed
description Primary hepatocellular carcinoma (HCC) in patients ＜30 years old is extremely rare. In younger patients, HCC develops against a background of persistent hepatitis B virus infection. We herein report a 23-year-old woman with HCC with all-negative hepatitis virus markers developing in an apparently healthy liver. Imaging studies showed a 50-mm hypervascular mass in segment 4 of the left liver lobe, compatible with HCC. The patient underwent surgical resection. A histological examination showed the presence of poorly differentiated HCC. The patient was diagnosed with HCC developing in a healthy liver. This is an extremely rare case of non-B non-C HCC.
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spelling pubmed-91773552022-07-05 Juvenile Hepatocellular Carcinoma in a Healthy Liver Onishi, Sachiyo Tajika, Masahiro Tanaka, Tsutomu Yamada, Keisaku Kamiya, Tomoyasu Natsume, Seiji Shimizu, Yasuhiro Niwa, Yasumasa Intern Med Case Report Primary hepatocellular carcinoma (HCC) in patients ＜30 years old is extremely rare. In younger patients, HCC develops against a background of persistent hepatitis B virus infection. We herein report a 23-year-old woman with HCC with all-negative hepatitis virus markers developing in an apparently healthy liver. Imaging studies showed a 50-mm hypervascular mass in segment 4 of the left liver lobe, compatible with HCC. The patient underwent surgical resection. A histological examination showed the presence of poorly differentiated HCC. The patient was diagnosed with HCC developing in a healthy liver. This is an extremely rare case of non-B non-C HCC. The Japanese Society of Internal Medicine 2021-10-19 2022-05-15 /pmc/articles/PMC9177355/ /pubmed/34670900 http://dx.doi.org/10.2169/internalmedicine.8305-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Onishi, Sachiyo
Tajika, Masahiro
Tanaka, Tsutomu
Yamada, Keisaku
Kamiya, Tomoyasu
Natsume, Seiji
Shimizu, Yasuhiro
Niwa, Yasumasa
Juvenile Hepatocellular Carcinoma in a Healthy Liver
title Juvenile Hepatocellular Carcinoma in a Healthy Liver
title_full Juvenile Hepatocellular Carcinoma in a Healthy Liver
title_fullStr Juvenile Hepatocellular Carcinoma in a Healthy Liver
title_full_unstemmed Juvenile Hepatocellular Carcinoma in a Healthy Liver
title_short Juvenile Hepatocellular Carcinoma in a Healthy Liver
title_sort juvenile hepatocellular carcinoma in a healthy liver
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177355/
https://www.ncbi.nlm.nih.gov/pubmed/34670900
http://dx.doi.org/10.2169/internalmedicine.8305-21
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