Rhabdomyolysis Caused by Gefitinib Overdose

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are common therapeutic agents for EGFR mutation-positive advanced non-small-cell lung cancer. There has been no report of rhabdomyolysis caused by an overdose of EGFR-TKIs. We herein review the existing literature on the subje...

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Autores principales: Obayashi, Shohei, Tomomatsu, Katsuyoshi, Urata, Mika, Tanaka, Jun, Niimi, Kyoko, Hayama, Naoki, Oguma, Tsuyoshi, Asano, Koichiro, Ito, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177374/
https://www.ncbi.nlm.nih.gov/pubmed/34707044
http://dx.doi.org/10.2169/internalmedicine.8168-21
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author Obayashi, Shohei
Tomomatsu, Katsuyoshi
Urata, Mika
Tanaka, Jun
Niimi, Kyoko
Hayama, Naoki
Oguma, Tsuyoshi
Asano, Koichiro
Ito, Yoko
author_facet Obayashi, Shohei
Tomomatsu, Katsuyoshi
Urata, Mika
Tanaka, Jun
Niimi, Kyoko
Hayama, Naoki
Oguma, Tsuyoshi
Asano, Koichiro
Ito, Yoko
author_sort Obayashi, Shohei
collection PubMed
description Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are common therapeutic agents for EGFR mutation-positive advanced non-small-cell lung cancer. There has been no report of rhabdomyolysis caused by an overdose of EGFR-TKIs. We herein review the existing literature on the subject and report a rare case of rhabdomyolysis due to an overdose of gefitinib, an EGFR-TKI.
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spelling pubmed-91773742022-07-05 Rhabdomyolysis Caused by Gefitinib Overdose Obayashi, Shohei Tomomatsu, Katsuyoshi Urata, Mika Tanaka, Jun Niimi, Kyoko Hayama, Naoki Oguma, Tsuyoshi Asano, Koichiro Ito, Yoko Intern Med Case Report Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are common therapeutic agents for EGFR mutation-positive advanced non-small-cell lung cancer. There has been no report of rhabdomyolysis caused by an overdose of EGFR-TKIs. We herein review the existing literature on the subject and report a rare case of rhabdomyolysis due to an overdose of gefitinib, an EGFR-TKI. The Japanese Society of Internal Medicine 2021-10-26 2022-05-15 /pmc/articles/PMC9177374/ /pubmed/34707044 http://dx.doi.org/10.2169/internalmedicine.8168-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Obayashi, Shohei
Tomomatsu, Katsuyoshi
Urata, Mika
Tanaka, Jun
Niimi, Kyoko
Hayama, Naoki
Oguma, Tsuyoshi
Asano, Koichiro
Ito, Yoko
Rhabdomyolysis Caused by Gefitinib Overdose
title Rhabdomyolysis Caused by Gefitinib Overdose
title_full Rhabdomyolysis Caused by Gefitinib Overdose
title_fullStr Rhabdomyolysis Caused by Gefitinib Overdose
title_full_unstemmed Rhabdomyolysis Caused by Gefitinib Overdose
title_short Rhabdomyolysis Caused by Gefitinib Overdose
title_sort rhabdomyolysis caused by gefitinib overdose
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177374/
https://www.ncbi.nlm.nih.gov/pubmed/34707044
http://dx.doi.org/10.2169/internalmedicine.8168-21
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