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Clinical pharmacokinetics of capecitabine and its metabolites in colorectal cancer patients

BACKGROUND: Capecitabine is one of the fluoropyrimidine anticancer agents which is extensively used in the management of colorectal cancer. We have noticed a discrepancy between the doses we are using in our patients and the recommended dosing regimen. Thus, this study aims to assess the pharmacokin...

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Detalles Bibliográficos
Autores principales: Alqahtani, Saeed, Alzaidi, Rawan, Alsultan, Abdullah, Asiri, Abdulaziz, Asiri, Yousif, Alsaleh, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177445/
https://www.ncbi.nlm.nih.gov/pubmed/35693432
http://dx.doi.org/10.1016/j.jsps.2022.02.019