Genome-wide mapping of individual replication fork velocities using nanopore sequencing

Little is known about replication fork velocity variations along eukaryotic genomes, since reference techniques to determine fork speed either provide no sequence information or suffer from low throughput. Here we present NanoForkSpeed, a nanopore sequencing-based method to map and extract the veloc...

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Detalles Bibliográficos
Autores principales: Theulot, Bertrand, Lacroix, Laurent, Arbona, Jean-Michel, Millot, Gael A., Jean, Etienne, Cruaud, Corinne, Pellet, Jade, Proux, Florence, Hennion, Magali, Engelen, Stefan, Lemainque, Arnaud, Audit, Benjamin, Hyrien, Olivier, Le Tallec, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177527/
https://www.ncbi.nlm.nih.gov/pubmed/35676270
http://dx.doi.org/10.1038/s41467-022-31012-0

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