Cargando…
The microRNA-3622 family at the 8p21 locus exerts oncogenic effects by regulating the p53-downstream gene network in prostate cancer progression
For human prostate cancer, the chromosome 8p21 locus, which contains NKX3.1 and the microRNA (miR)-3622 family (miR-3622a/b), is a frequently deleted region. Thus, miR-3622 is proposed as a suppressor for prostate cancer, but its role remains debatable. In the present study, we found that expression...
Autores principales: | Zhang, Yue, Xu, Zhifang, Wen, Wen, Liu, Zhichao, Zhang, Chao, Li, Ming, Hu, Fengping, Wei, Shi, Bae, Sejong, Zhou, Jiangbing, Liu, Runhua, Wang, Lizhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177620/ https://www.ncbi.nlm.nih.gov/pubmed/35501464 http://dx.doi.org/10.1038/s41388-022-02289-8 |
Ejemplares similares
-
Tumor suppressor role of miR-3622b-5p in ERBB2-positive cancer
por: Lu, Mingjie, et al.
Publicado: (2017) -
Epigenetic regulation of EIF4A1 through DNA methylation and an oncogenic role of eIF4A1 through BRD2 signaling in prostate cancer
por: Wang, Chao, et al.
Publicado: (2022) -
Mutant p53 exerts oncogenic functions by modulating cancer cell metabolism
por: Zhou, Ge, et al.
Publicado: (2014) -
Intracellular CD24 disrupts the ARF–NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation
por: Wang, Lizhong, et al.
Publicado: (2015) -
Inhibition of HIV early replication by the p53 and its downstream gene p21
por: Shi, Binshan, et al.
Publicado: (2018)