Feasibility and limitations of cultured skin fibroblasts for germline genetic testing in hematologic disorders

To avoid acquired variants found in the blood, cultured skin fibroblasts are a recommended DNA source for germline genetic testing in patients with hematologic disorders, but data are lacking regarding practicality and limitations. We conducted a retrospective cohort study of 350 subjects with hemat...

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Detalles Bibliográficos
Autores principales: DeRoin, Lia, Cavalcante de Andrade Silva, Marcela, Petras, Kristin, Arndt, Kelly, Phillips, Nathaniel, Wanjari, Pankhuri, Subramanian, Hari Prasanna, Montes, David, McElherne, James, Theissen, Megan, Briese, Renee, Das, Soma, Godley, Lucy A., Segal, Jeremy, del Gaudio, Daniela, Fitzpatrick, Carrie, Churpek, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177640/
https://www.ncbi.nlm.nih.gov/pubmed/35419889
http://dx.doi.org/10.1002/humu.24374

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