Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals

Despite recent success in hepatitis C virus (HCV) treatment using antivirals, an HCV vaccine is still needed to prevent reinfections in treated patients, to avert the emergence of drug-resistant strains, and to provide protection for people with no access to the antiviral therapeutics. The early pro...

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Detalles Bibliográficos
Autores principales: Bozhanova, Nina G., Flyak, Andrew I., Brown, Benjamin P., Ruiz, Stormy E., Salas, Jordan, Rho, Semi, Bombardi, Robin G., Myers, Luke, Soto, Cinque, Bailey, Justin R., Crowe, James E., Bjorkman, Pamela J., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177688/
https://www.ncbi.nlm.nih.gov/pubmed/35676279
http://dx.doi.org/10.1038/s41467-022-30865-9

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