SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1

A recent mutation analysis suggested that Non-Structural Protein 6 (NSP6) of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a key determinant of the viral pathogenicity. Here, by transcriptome analysis, we demonstrated that the inflammasome-related NOD-like receptor signaling wa...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Liu, Yingzhi, Huang, Ziheng, Xu, Wenye, Hu, Wei, Yi, Lina, Liu, Zhe, Chan, Hung, Zeng, Judeng, Liu, Xiaodong, Chen, Huarong, Yu, Jun, Chan, Francis Ka Leung, Ng, Siew Chien, Wong, Sunny Hei, Wang, Maggie Haitian, Gin, Tony, Joynt, Gavin Matthew, Hui, David Shu Cheong, Zou, Xuan, Shu, Yuelong, Cheng, Christopher Hon Ki, Fang, Shisong, Luo, Huanle, Lu, Jing, Chan, Matthew Tak Vai, Zhang, Lin, Wu, William Ka Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177730/
https://www.ncbi.nlm.nih.gov/pubmed/34997207
http://dx.doi.org/10.1038/s41418-021-00916-7

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