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Integrative PheWAS analysis in risk categorization of major depressive disorder and identifying their associations with genetic variants using a latent topic model approach

Major depressive disorder (MDD) is the most prevalent mental disorder that constitutes a major public health problem. A tool for predicting the risk of MDD could assist with the early identification of MDD patients and targeted interventions to reduce the risk. We aimed to derive a risk prediction t...

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Detalles Bibliográficos
Autores principales: Meng, Xiangfei, Wang, Michelle, O’Donnell, Kieran J., Caron, Jean, Meaney, Michael J., Li, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177831/
https://www.ncbi.nlm.nih.gov/pubmed/35676267
http://dx.doi.org/10.1038/s41398-022-02015-8

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