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Integrative PheWAS analysis in risk categorization of major depressive disorder and identifying their associations with genetic variants using a latent topic model approach
Major depressive disorder (MDD) is the most prevalent mental disorder that constitutes a major public health problem. A tool for predicting the risk of MDD could assist with the early identification of MDD patients and targeted interventions to reduce the risk. We aimed to derive a risk prediction t...
Autores principales: | Meng, Xiangfei, Wang, Michelle, O’Donnell, Kieran J., Caron, Jean, Meaney, Michael J., Li, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177831/ https://www.ncbi.nlm.nih.gov/pubmed/35676267 http://dx.doi.org/10.1038/s41398-022-02015-8 |
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