Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET

Retinoic acid-inducible gene (RIG)-I is an essential innate immune sensor that recognises pathogen RNAs and induces interferon (IFN) production. However, little is known about how host proteins regulate RIG-I activation. Here, we show that leukocyte cell-derived chemotaxin 2 (LECT2), a hepatokine an...

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Detalles Bibliográficos
Autores principales: Shirasaki, Takayoshi, Yamagoe, Satoshi, Shimakami, Tetsuro, Murai, Kazuhisa, Imamura, Ryu, Ishii, Kiyo-Aki, Takayama, Hiroaki, Matsumoto, Yukako, Tajima-Shirasaki, Natsumi, Nagata, Naoto, Shimizu, Ryogo, Yamanaka, Souma, Abe, Atsushi, Omura, Hitoshi, Kawaguchi, Kazunori, Okada, Hikari, Yamashita, Taro, Yoshikawa, Tomoki, Takimoto, Kazuhiro, Taharaguchi, Motoko, Takatsuka, Shogo, Miyazaki, Yoshitsugu, Tamai, Toshikatsu, Tanabe, Yamato, Kurachi, Makoto, Yamamoto, Yasuhiko, Kaneko, Shuichi, Matsumoto, Kunio, Takamura, Toshinari, Honda, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177837/
https://www.ncbi.nlm.nih.gov/pubmed/35676290
http://dx.doi.org/10.1038/s41467-022-30879-3

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