Ligand recognition and biased agonism of the D1 dopamine receptor

Dopamine receptors are widely distributed in the central nervous system and are important therapeutic targets for treatment of various psychiatric and neurological diseases. Here, we report three cryo-electron microscopy structures of the D1 dopamine receptor (D1R)-Gs complex bound to two agonists,...

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Detalles Bibliográficos
Autores principales: Teng, Xiao, Chen, Sijia, Nie, Yingying, Xiao, Peng, Yu, Xiao, Shao, Zhenhua, Zheng, Sanduo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177848/
https://www.ncbi.nlm.nih.gov/pubmed/35676276
http://dx.doi.org/10.1038/s41467-022-30929-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177848/
https://www.ncbi.nlm.nih.gov/pubmed/35676276
http://dx.doi.org/10.1038/s41467-022-30929-w

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