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The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome

The segmented negative-sense RNA genome of influenza A virus is assembled into ribonucleoprotein complexes (RNP) with viral RNA-dependent RNA polymerase and nucleoprotein (NP). It is in the context of these RNPs that the polymerase transcribes and replicates viral RNA (vRNA). Host acidic nuclear pho...

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Detalles Bibliográficos
Autores principales: Wang, Fangzheng, Sheppard, Carol M, Mistry, Bhakti, Staller, Ecco, Barclay, Wendy S, Grimes, Jonathan M, Fodor, Ervin, Fan, Haitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177957/
https://www.ncbi.nlm.nih.gov/pubmed/35639917
http://dx.doi.org/10.1093/nar/gkac410