RNF4 controls the extent of replication fork reversal to preserve genome stability

Replication fork reversal occurs via a two-step process that entails reversal initiation and reversal extension. DNA topoisomerase IIalpha (TOP2A) facilitates extensive fork reversal, on one hand through resolving the topological stress generated by the initial reversal, on the other hand via its ro...

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Detalles Bibliográficos
Autores principales: Ding, Linli, Luo, Yi, Tian, Tian, Chen, Xu, Yang, Yulan, Bu, Min, Han, Jinhua, Yang, Bing, Yan, Haiyan, Liu, Ting, Wu, Mengjie, Zhang, Guofei, Xu, Yipeng, Zhu, Shaoxing, Huen, Michael S Y, Mao, Genxiang, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177969/
https://www.ncbi.nlm.nih.gov/pubmed/35640614
http://dx.doi.org/10.1093/nar/gkac447

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