Cooperation between intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly

Transcription elongation factor Spt6 associates with RNA polymerase II (Pol II) and acts as a histone chaperone, which promotes the reassembly of nucleosomes following the passage of Pol II. The precise mechanism of nucleosome reassembly mediated by Spt6 remains unclear. In this study, we used a hyb...

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Detalles Bibliográficos
Autores principales: Kasiliauskaite, Aiste, Kubicek, Karel, Klumpler, Tomas, Zanova, Martina, Zapletal, David, Koutna, Eliska, Novacek, Jiri, Stefl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177984/
https://www.ncbi.nlm.nih.gov/pubmed/35640611
http://dx.doi.org/10.1093/nar/gkac451

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