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N-oleoylethanolamide treatment of lymphoblasts deficient in Tafazzin improves cell growth and mitochondrial morphology and dynamics

Barth syndrome (BTHS) is caused by mutations in the TAZ gene encoding the cardiolipin remodeling enzyme, Tafazzin. The study objective was to quantitatively examine growth characteristics and mitochondrial morphology of transformed lymphoblast cell lines derived from five patients with BTHS relative...

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Detalles Bibliográficos
Autores principales: Chan, John Z., Fernandes, Maria F., Steckel, Klaudia E., Bradley, Ryan M., Hashemi, Ashkan, Groh, Mishi R., Sciaini, German, Stark, Ken D., Duncan, Robin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178007/
https://www.ncbi.nlm.nih.gov/pubmed/35676289
http://dx.doi.org/10.1038/s41598-022-13463-z