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N-oleoylethanolamide treatment of lymphoblasts deficient in Tafazzin improves cell growth and mitochondrial morphology and dynamics
Barth syndrome (BTHS) is caused by mutations in the TAZ gene encoding the cardiolipin remodeling enzyme, Tafazzin. The study objective was to quantitatively examine growth characteristics and mitochondrial morphology of transformed lymphoblast cell lines derived from five patients with BTHS relative...
Autores principales: | Chan, John Z., Fernandes, Maria F., Steckel, Klaudia E., Bradley, Ryan M., Hashemi, Ashkan, Groh, Mishi R., Sciaini, German, Stark, Ken D., Duncan, Robin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178007/ https://www.ncbi.nlm.nih.gov/pubmed/35676289 http://dx.doi.org/10.1038/s41598-022-13463-z |
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