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The topoisomerase 3 zinc finger domain cooperates with the RMI1 scaffold to promote stable association of the BTR complex to recombination intermediates in the Caenorhabditis elegans germline

Homologous recombination is the predominant DNA repair pathway used in the gonad. Of the excess DNA double-strand breaks formed in meiosis, only a subset matures into crossovers, with the remainder repaired as non-crossovers. The conserved BTR complex (comprising Bloom helicase, topoisomerase 3 and...

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Detalles Bibliográficos
Autores principales:	Dello Stritto, Maria Rosaria, Vojtassakova, Nina, Velkova, Maria, Hamminger, Patricia, Ulm, Patricia, Jantsch, Verena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178014/ https://www.ncbi.nlm.nih.gov/pubmed/35639927 http://dx.doi.org/10.1093/nar/gkac408

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