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Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome

Adipose tissue, one type of loose connective tissue in the human body, maintains the primary task of energy storage. Adipose tissue is not only an energy reservoir but also plays a vital role as the largest endocrine organ of the whole body via releasing a variety of adipokines, which participate in...

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Autores principales: Chen, Peipei, Jia, Rui, Liu, Yuanyuan, Cao, Mingya, Zhou, Liang, Zhao, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178087/
https://www.ncbi.nlm.nih.gov/pubmed/35692386
http://dx.doi.org/10.3389/fendo.2022.881684
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author Chen, Peipei
Jia, Rui
Liu, Yuanyuan
Cao, Mingya
Zhou, Liang
Zhao, Zhiming
author_facet Chen, Peipei
Jia, Rui
Liu, Yuanyuan
Cao, Mingya
Zhou, Liang
Zhao, Zhiming
author_sort Chen, Peipei
collection PubMed
description Adipose tissue, one type of loose connective tissue in the human body, maintains the primary task of energy storage. Adipose tissue is not only an energy reservoir but also plays a vital role as the largest endocrine organ of the whole body via releasing a variety of adipokines, which participate in many pathophysiological processes, such as energy metabolism regulation, glucose and lipid metabolism, and inflammation. Polycystic ovary syndrome (PCOS) is a disorder that mainly involves the female reproductive system, affecting women of childbearing age particularly. Insulin resistance (IR) and hyperandrogenemia (HA) have been implicated as a critical link involving the etiology and outcome of PCOS. A great deal of studies has bridged the gap between adipokines (such as Adiponectin, Chemerin, Metrnl, Apelin, Resistin, Visfatin, Leptin, Vaspin, Lipocalin 2, and Omentin) and reproductive fitness. In this review, we will focus on the adipokines’ functions on PCOS and come up with some points of view on the basis of current research.
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spelling pubmed-91780872022-06-10 Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome Chen, Peipei Jia, Rui Liu, Yuanyuan Cao, Mingya Zhou, Liang Zhao, Zhiming Front Endocrinol (Lausanne) Endocrinology Adipose tissue, one type of loose connective tissue in the human body, maintains the primary task of energy storage. Adipose tissue is not only an energy reservoir but also plays a vital role as the largest endocrine organ of the whole body via releasing a variety of adipokines, which participate in many pathophysiological processes, such as energy metabolism regulation, glucose and lipid metabolism, and inflammation. Polycystic ovary syndrome (PCOS) is a disorder that mainly involves the female reproductive system, affecting women of childbearing age particularly. Insulin resistance (IR) and hyperandrogenemia (HA) have been implicated as a critical link involving the etiology and outcome of PCOS. A great deal of studies has bridged the gap between adipokines (such as Adiponectin, Chemerin, Metrnl, Apelin, Resistin, Visfatin, Leptin, Vaspin, Lipocalin 2, and Omentin) and reproductive fitness. In this review, we will focus on the adipokines’ functions on PCOS and come up with some points of view on the basis of current research. Frontiers Media S.A. 2022-05-26 /pmc/articles/PMC9178087/ /pubmed/35692386 http://dx.doi.org/10.3389/fendo.2022.881684 Text en Copyright © 2022 Chen, Jia, Liu, Cao, Zhou and Zhao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Chen, Peipei
Jia, Rui
Liu, Yuanyuan
Cao, Mingya
Zhou, Liang
Zhao, Zhiming
Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome
title Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome
title_full Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome
title_fullStr Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome
title_full_unstemmed Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome
title_short Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome
title_sort progress of adipokines in the female reproductive system: a focus on polycystic ovary syndrome
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178087/
https://www.ncbi.nlm.nih.gov/pubmed/35692386
http://dx.doi.org/10.3389/fendo.2022.881684
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