Iron overload and impaired iron handling contribute to the dystrophic pathology in models of Duchenne muscular dystrophy

BACKGROUND: Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular dystrophies. To our knowledge, the distribution of iron, an important modulator of oxidative stress,...

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Detalles Bibliográficos
Autores principales: Alves, Francesca M., Kysenius, Kai, Caldow, Marissa K., Hardee, Justin P., Chung, Jin D., Trieu, Jennifer, Hare, Dominic J., Crouch, Peter J., Ayton, Scott, Bush, Ashley I., Lynch, Gordon S., Koopman, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178167/
https://www.ncbi.nlm.nih.gov/pubmed/35249268
http://dx.doi.org/10.1002/jcsm.12950

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