Cargando…
Neu1 Is Released From Activated Microglia, Stimulating Microglial Phagocytosis and Sensitizing Neurons to Glutamate
Neuraminidase 1 (Neu1) hydrolyses terminal sialic acid residues from glycoproteins and glycolipids, and is normally located in lysosomes, but can be released onto the surface of activated myeloid cells and microglia. We report that endotoxin/lipopolysaccharide-activated microglia released Neu1 into...
Autores principales: | Allendorf, David H., Brown, Guy C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178234/ https://www.ncbi.nlm.nih.gov/pubmed/35693885 http://dx.doi.org/10.3389/fncel.2022.917884 |
Ejemplares similares
-
Activated microglia desialylate their surface, stimulating complement receptor 3‐mediated phagocytosis of neurons
por: Allendorf, David H., et al.
Publicado: (2019) -
LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation
por: Reid, Kyle M., et al.
Publicado: (2023) -
Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
por: Sierra, Amanda, et al.
Publicado: (2013) -
Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia
por: Paetau, Sonja, et al.
Publicado: (2017) -
Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration
por: Puigdellívol, Mar, et al.
Publicado: (2020)