Avian Leucosis Virus-Host Interaction: The Involvement of Host Factors in Viral Replication

Avian leukosis virus (ALV) causes various diseases associated with tumor formation and decreased fertility. Moreover, ALV induces severe immunosuppression, increasing susceptibility to other microbial infections and the risk of failure in subsequent vaccination against other diseases. There is growi...

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Detalles Bibliográficos
Autores principales: Tang, Shuang, Li, Jie, Chang, Yung-Fu, Lin, Wencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178239/
https://www.ncbi.nlm.nih.gov/pubmed/35693802
http://dx.doi.org/10.3389/fimmu.2022.907287
Descripción
Sumario:Avian leukosis virus (ALV) causes various diseases associated with tumor formation and decreased fertility. Moreover, ALV induces severe immunosuppression, increasing susceptibility to other microbial infections and the risk of failure in subsequent vaccination against other diseases. There is growing evidence showing the interaction between ALV and the host. In this review, we will survey the present knowledge of the involvement of host factors in the important molecular events during ALV infection and discuss the futuristic perspectives from this angle.

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