Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

Autosomal recessive IRF7 deficiency was previously reported in three patients with single critical influenza or COVID-19 pneumonia episodes. The patients’ fibroblasts and plasmacytoid dendritic cells produced no detectable type I and III IFNs, except IFN-β. Having discovered four new patients, we de...

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Detalles Bibliográficos
Autores principales: Campbell, Tessa Mollie, Liu, Zhiyong, Zhang, Qian, Moncada-Velez, Marcela, Covill, Laura E., Zhang, Peng, Alavi Darazam, Ilad, Bastard, Paul, Bizien, Lucy, Bucciol, Giorgia, Lind Enoksson, Sara, Jouanguy, Emmanuelle, Karabela, Şemsi Nur, Khan, Taushif, Kendir-Demirkol, Yasemin, Arias, Andres Augusto, Mansouri, Davood, Marits, Per, Marr, Nico, Migeotte, Isabelle, Moens, Leen, Ozcelik, Tayfun, Pellier, Isabelle, Sendel, Anton, Şenoğlu, Sevtap, Shahrooei, Mohammad, Smith, C.I. Edvard, Vandernoot, Isabelle, Willekens, Karen, Kart Yaşar, Kadriye, Bergman, Peter, Abel, Laurent, Cobat, Aurélie, Casanova, Jean-Laurent, Meyts, Isabelle, Bryceson, Yenan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178406/
https://www.ncbi.nlm.nih.gov/pubmed/35670811
http://dx.doi.org/10.1084/jem.20220202

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