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Reduced Immunogenicity of Intraparenchymal Delivery of Adeno-Associated Virus Serotype 2 Vectors: Brief Overview

Pre existing immunity to adeno-associated virus (AAV) poses a concern in AAV vector–mediated gene therapy. Localized administration of low doses of carefully chosen AAV serotypes can mitigate the risk of an immune response. This article will illustrate the low risk of immune response to AAV serotype...

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Detalles Bibliográficos
Autores principales:	Hwu, Wuh-Liang, Muramatsu, Shin-ichi, Gidoni-Ben-Zeev, Bruria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2022
Materias:	Genetics & Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178513/ https://www.ncbi.nlm.nih.gov/pubmed/34551695 http://dx.doi.org/10.2174/1566523221666210922155413

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