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Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life

BACKGROUND AND AIM: Calves have increased morbidity and mortality rates after dystocia. One cause is pain during birth, which reduces their colostrum intake. The administration of nonsteroidal anti-inflammatory drugs (NSAIDs) may break this causality. This study aimed to determine the consequences o...

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Autores principales: Kunz, Fabian, Sendag, Sait, Yildiz, Mehmet, Failing, Klaus, Wehrend, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178569/
https://www.ncbi.nlm.nih.gov/pubmed/35698526
http://dx.doi.org/10.14202/vetworld.2022.981-985
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author Kunz, Fabian
Sendag, Sait
Yildiz, Mehmet
Failing, Klaus
Wehrend, Axel
author_facet Kunz, Fabian
Sendag, Sait
Yildiz, Mehmet
Failing, Klaus
Wehrend, Axel
author_sort Kunz, Fabian
collection PubMed
description BACKGROUND AND AIM: Calves have increased morbidity and mortality rates after dystocia. One cause is pain during birth, which reduces their colostrum intake. The administration of nonsteroidal anti-inflammatory drugs (NSAIDs) may break this causality. This study aimed to determine the consequences of a single administration of the NSAID meloxicam to dystocia calves after birth. MATERIALS AND METHODS: Fifty Holstein–Friesian calves born with dystocia from four dairy cattle farms were included in this study. The animals were randomized into two groups. The animals in Group I (n=25, treatment group) received subcutaneous 0.5 mg meloxicam/kg body weight 2-8 h after birth. The animals in Group II (n=25, control group) received a control substance (Amynin(®), bovine infusion solution, Merial) with the same volume. The newborn calves were clinically examined on the 1(st) and 10(th) days of life. The information regarding the days in between was gathered by questioning the farmer. RESULTS: There was a significant difference (p=0.04) only in calves with thin, mushy fecal consistency on the 10(th) day in the treatment group compared with the control group. Moreover, meloxicam had no effect on dystocia calves. CONCLUSION: Since NSAID administration did not produce a significant clinical effect, its necessity is questionable. Further studies should examine how modifying its application time would have an effect. The primary indicators of well-being, such as pain indicators in the blood, were not measured; however, these should be considered in subsequent studies.
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spelling pubmed-91785692022-06-12 Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life Kunz, Fabian Sendag, Sait Yildiz, Mehmet Failing, Klaus Wehrend, Axel Vet World Research Article BACKGROUND AND AIM: Calves have increased morbidity and mortality rates after dystocia. One cause is pain during birth, which reduces their colostrum intake. The administration of nonsteroidal anti-inflammatory drugs (NSAIDs) may break this causality. This study aimed to determine the consequences of a single administration of the NSAID meloxicam to dystocia calves after birth. MATERIALS AND METHODS: Fifty Holstein–Friesian calves born with dystocia from four dairy cattle farms were included in this study. The animals were randomized into two groups. The animals in Group I (n=25, treatment group) received subcutaneous 0.5 mg meloxicam/kg body weight 2-8 h after birth. The animals in Group II (n=25, control group) received a control substance (Amynin(®), bovine infusion solution, Merial) with the same volume. The newborn calves were clinically examined on the 1(st) and 10(th) days of life. The information regarding the days in between was gathered by questioning the farmer. RESULTS: There was a significant difference (p=0.04) only in calves with thin, mushy fecal consistency on the 10(th) day in the treatment group compared with the control group. Moreover, meloxicam had no effect on dystocia calves. CONCLUSION: Since NSAID administration did not produce a significant clinical effect, its necessity is questionable. Further studies should examine how modifying its application time would have an effect. The primary indicators of well-being, such as pain indicators in the blood, were not measured; however, these should be considered in subsequent studies. Veterinary World 2022-04 2022-04-19 /pmc/articles/PMC9178569/ /pubmed/35698526 http://dx.doi.org/10.14202/vetworld.2022.981-985 Text en Copyright: © Kunz, et al. https://creativecommons.org/licenses/by/4.0/Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Kunz, Fabian
Sendag, Sait
Yildiz, Mehmet
Failing, Klaus
Wehrend, Axel
Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life
title Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life
title_full Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life
title_fullStr Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life
title_full_unstemmed Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life
title_short Effect of a single meloxicam administration on newborn Holstein–Friesian dystocia calves: Field results from the first 10 days of life
title_sort effect of a single meloxicam administration on newborn holstein–friesian dystocia calves: field results from the first 10 days of life
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178569/
https://www.ncbi.nlm.nih.gov/pubmed/35698526
http://dx.doi.org/10.14202/vetworld.2022.981-985
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