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Biological Evaluation, Molecular Docking Analyses, and ADME Profiling of Certain New Quinazolinones as Anti-colorectal Agents

[Image: see text] Colorectal carcinogenesis is a complex process, which is linked to dysregulation of human secretory phospholipases A(2) (hsPLA(2)-G-IIA, hsPLA(2)-G-V, and hsPLA(2)-G-X), proteases (cathepsin-B, collagenase, thrombin, elastase, and trypsin), carbohydrate hydrolyzing enzymes (α-amyla...

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Detalles Bibliográficos
Autores principales:	El-Sayed, Nahed N. E., Almaneai, Norah M., Ben Bacha, Abir, El-Ashrey, Mohamed K., Al-Zaben, Maha I., Almarhoon, Zainab M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178606/ https://www.ncbi.nlm.nih.gov/pubmed/35694504 http://dx.doi.org/10.1021/acsomega.2c00812

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