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A study on DNA methylation modifying natural compounds identified EGCG for induction of IFI16 gene expression related to the innate immune response in cancer cells

Innate immune sensor IFN-induced protein 16 (IFI16) exhibits anti-inflammatory effects via IFNβ and IFN-stimulated gene (ISG)15 induction in cancer cells. Epigallocatechin gallate (EGCG) is a potent natural DNA methyltransferase inhibitor (DNMTi). Previous studies revealed that conventional DNMTis,...

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Detalles Bibliográficos
Autores principales:	Khan, Mohammad Imran, Nur, Suza Mohammad, Abdulaal, Wesam H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178671/ https://www.ncbi.nlm.nih.gov/pubmed/35707762 http://dx.doi.org/10.3892/ol.2022.13339

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