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Transcriptional Tuning of Mevalonate Pathway Enzymes to Identify the Impact on Limonene Production in Escherichia coli

[Image: see text] Heterologous production of limonene in microorganisms through the mevalonate (MVA) pathway has traditionally imposed metabolic burden and reduced cell fitness, where imbalanced stoichiometries among sequential enzymes result in the accumulation of toxic intermediates. Although prio...

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Detalles Bibliográficos
Autores principales: Shin, Jonghyeon, South, Eric J., Dunlop, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178717/
https://www.ncbi.nlm.nih.gov/pubmed/35694509
http://dx.doi.org/10.1021/acsomega.2c00483