Cargando…

Transcriptional Tuning of Mevalonate Pathway Enzymes to Identify the Impact on Limonene Production in Escherichia coli

[Image: see text] Heterologous production of limonene in microorganisms through the mevalonate (MVA) pathway has traditionally imposed metabolic burden and reduced cell fitness, where imbalanced stoichiometries among sequential enzymes result in the accumulation of toxic intermediates. Although prio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Jonghyeon, South, Eric J., Dunlop, Mary J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178717/ https://www.ncbi.nlm.nih.gov/pubmed/35694509 http://dx.doi.org/10.1021/acsomega.2c00483

Ejemplares similares

Cell-free biosynthesis of limonene using enzyme-enriched Escherichia coli lysates
por: Dudley, Quentin M, et al.
Publicado: (2019)

Visualization of a Limonene Synthesis Metabolon Inside Living Bacteria by Hyperspectral SRS Microscopy
por: Zhang, Jing, et al.
Publicado: (2022)

Combinatory optimization of chromosomal integrated mevalonate pathway for β-carotene production in Escherichia coli
por: Ye, Lijun, et al.
Publicado: (2016)

A Gram-Scale Limonene Production Process with Engineered Escherichia coli
por: Rolf, Jascha, et al.
Publicado: (2020)

Strategic approach of multifaceted antibacterial mechanism of limonene traced in Escherichia coli
por: Gupta, Akshi, et al.
Publicado: (2021)

Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2).
por: Kawata, S., et al.
Publicado: (1994)

Isoprene production by Escherichia coli through the exogenous mevalonate pathway with reduced formation of fermentation byproducts
por: Kim, Jung-Hun, et al.
Publicado: (2016)

Synthesis of Heterologous Mevalonic Acid Pathway Enzymes in Clostridium ljungdahlii for the Conversion of Fructose and of Syngas to Mevalonate and Isoprene
por: Diner, Bruce A., et al.
Publicado: (2017)

Increased carvone production in Escherichia coli by balancing limonene conversion enzyme expression via targeted quantification concatamer proteome analysis
por: Yoshida, Erika, et al.
Publicado: (2021)

Directed evolution of mevalonate kinase in Escherichia coli by random mutagenesis for improved lycopene
por: Chen, Hailin, et al.
Publicado: (2018)

Correction: Directed evolution of mevalonate kinase in Escherichia coli by random mutagenesis for improved lycopene
por: Chen, Hailin, et al.
Publicado: (2019)

Enzymatic Hydrolysis of Textile and Cardboard Waste as a Glucose Source for the Production of Limonene in Escherichia coli
por: Zebec, Žiga, et al.
Publicado: (2022)

Study of messenger RNA inactivation and protein degradation in an Escherichia coli cell-free expression system
por: Shin, Jonghyeon, et al.
Publicado: (2010)

Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression
por: Wang, I-Han, et al.
Publicado: (2020)

Microbial production of mevalonate by recombinant Escherichia coli using acetic acid as a carbon source
por: Xu, Xin, et al.
Publicado: (2017)

Differential Mechanism of Escherichia coli Inactivation by (+)-Limonene as a Function of Cell Physiological State and Drug's Concentration
por: Chueca, Beatriz, et al.
Publicado: (2014)

Programming Escherichia coli to function as a digital display
por: Shin, Jonghyeon, et al.
Publicado: (2020)

Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase
por: Chen, Chun-Liang, et al.
Publicado: (2020)

The mevalonate pathway in C. Elegans
por: Rauthan, Manish, et al.
Publicado: (2011)

Fine tuning the glycolytic flux ratio of EP-bifido pathway for mevalonate production by enhancing glucose-6-phosphate dehydrogenase (Zwf) and CRISPRi suppressing 6-phosphofructose kinase (PfkA) in Escherichia coli
por: Li, Ying, et al.
Publicado: (2021)

Neuroprotective Potential of Limonene and Limonene Containing Natural Products
por: Eddin, Lujain Bader, et al.
Publicado: (2021)

Efficient Synthesis of (R)-(+)-Perillyl Alcohol From (R)-(+)-Limonene Using Engineered Escherichia coli Whole Cell Biocatalyst
por: Sun, Chao, et al.
Publicado: (2022)

Rationally optimized generation of integrated Escherichia coli with stable and high yield lycopene biosynthesis from heterologous mevalonate (MVA) and lycopene expression pathways
por: Hussain, Muhammad Hammad, et al.
Publicado: (2021)

Genomic variations of the mevalonate pathway in porokeratosis
por: Zhang, Zhenghua, et al.
Publicado: (2015)

The Mevalonate Pathway Is Indispensable for Adipocyte Survival
por: Yeh, Yu-Sheng, et al.
Publicado: (2018)

Consequences of blunting the mevalonate pathway in cancer identified by a pluri-omics approach
por: Goulitquer, Sophie, et al.
Publicado: (2018)

HSF1 Regulates Mevalonate and Cholesterol Biosynthesis Pathways
por: Kang, Hyeji, et al.
Publicado: (2019)

Stromal regulation of prostate cancer cell growth by mevalonate pathway enzymes HMGCS1 and HMGCR
por: Ashida, Shingo, et al.
Publicado: (2017)

Inhibiting mevalonate pathway enzymes increases stromal cell resilience to a cholesterol-dependent cytolysin
por: Griffin, Sholeem, et al.
Publicado: (2017)

Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway
por: Pütter, Katharina M., et al.
Publicado: (2017)

Antidiabetic drug metformin suppresses tumorigenesis through inhibition of mevalonate pathway enzyme HMGCS1
por: Chen, Yiyan, et al.
Publicado: (2022)

3′-UTR engineering to improve soluble expression and fine-tuning of activity of cascade enzymes in Escherichia coli
por: Song, Ji-Won, et al.
Publicado: (2016)

Improving heterologous membrane protein production in Escherichia coli by combining transcriptional tuning and codon usage algorithms
por: Claassens, Nico J., et al.
Publicado: (2017)

ENZYME BIOSYNTHESIS IN ESCHERICHIA COLI
por: Weinbaum, George, et al.
Publicado: (1959)

Microsecond fingerprint stimulated Raman spectroscopic imaging by ultrafast tuning and spatial-spectral learning
por: Lin, Haonan, et al.
Publicado: (2021)

Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli
por: Iyer, Mahesh S., et al.
Publicado: (2021)

Evidence of a Novel Mevalonate Pathway in Archaea
por: Vinokur, Jeffrey M., et al.
Publicado: (2014)

Correction: Genomic variations of the mevalonate pathway in porokeratosis
por: Zhang, Zhenghua, et al.
Publicado: (2016)

Control of the innate immune response by the mevalonate pathway
por: Akula, Murali K., et al.
Publicado: (2016)

Activation of the plant mevalonate pathway by extracellular ATP
por: Cho, Sung-Hwan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vhv636jiatrb07uu1jhosrc5nf